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INTRODUCTION
OUTLINE
  • A01 Molecular Control
  • A02 Structure Construction
  • A03 Function Exploration
ORGANIZATION
  • A01 Molecular Control
  • A02 Structure Construction
  • A03 Function Exploration
MEETINGS
ACHIEVEMENTS
TOPICS
PUBLICATIONS
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Profile
Yukio NAGASAKI,
Professor
Faculty of Pure and Applied Sciences, University of Tsukuba
Contact Information
Address: Tennoudai 1-1-1, Tsukuba, Ibaraki 305-8573, Japan
E-mail: yukio“at”nagalabo.jp (but replace “at” with “@”)
Personal Homepage： http://www.ims.tsukuba.ac.jp/~nagasaki_lab/indexe.htm
Fields of Interest
Polymer Chemistry, Biofunctional Materials, Nanomedicine
Professional Experience
1982-1987 Graduate research, Science University of Tokyo (Supervisor: Prof.Teiji Tsukuta)
1987-1993 Assistant Professor, Science University of Tokyo
1993-1999 Lecturer, Science University of Tokyo
1999-2003 Associate Professor, Science University of Tokyo
2003-2004 Professor, Science University of Tokyo
2004- Professor, University of Tsukuba
2004-2011 Principal Investigator, Tsukuba Interdisciplinary Materials Science, U.Tsukuba
2006-2011 Principal Investigator, Tsukuba Advanced Research Alliance, U. Tsukuba
2007- Adjunct Professor, Department of Medical Sciences, U. Tsukuba
2007-2011 Guest Professor, Research Institute for Science and Technology, Tokyo University of Science
2007- Principal Investigator, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science
2011- Principal Investigator, Pre-strategic Initiative (Research Project) at University of Tsukuba
2013- Adjunct Professor, Center for Research in Isotopes and Environmental Dynamics (CRiED)
Education
Ph.D. 1987, Science University of Tokyo
Membership of Academic Societies
Chemical Society of Japan, Polymer Society of Japan, Biomaterials Society of Japan, Pharmaceutical Society of Japan, DDS Society of Japan, Cancer Society of Japan, Society for Free Radical Research, Japan, The Japanese Pharmacological Society, Artificial Organ Society of Japan, The Japanese Society of Neutron Capture Therapy, The Japanese Society of Gastroenterology, The Japan Photodynamic Association, The Japanese Society of Magnetic Resonance in Medicine, Anti-aging Society of Japan, American Chemical Society, Controlled Release Society, Society for Biomaterials, American Association of Cancer Research, European Renal Association-European Dialysis and Transplant Association, The American Society of Gene & Cell Therapy, Japanese Society of Anti-aging Society, Japan Society for Dementia Research, American Association of Pharmaceutical Scientists
Awards & Honors
  1. SPSJ Mitsubishi Chemical Award (2011)
Research Project
Design of Silica-containing Redox Nanoparticles for High Performance Peritoneal Dialysis
Selected Publications
  1. Kamimura, M., Furukawa, T., Akiyama, S., Nagasaki, Y.
    “Enhanced Intracellular Drug Delivery of Ph-Sensitive Doxorubicin/Poly(Ethylene Glycol)-Block-Poly(4-Vinylbenzylphosphonate) Nanoparticles in Multi-Drug Resistant Human Epidermoid KB Carcinoma Cells”,
    Biomater. Sci., 1, 361-367 (2013). (DOI:10.1039/C2BM00156J)

  2. Chonpathompikunlert, P., Fan, C.-H., Ozaki, Y., Yoshitomi, T., Yeh,C.-K., Nagasaki, Y.
    “Redox Nanoparticle Treatment Protects Against Neurological Deficit in Focused Ultrasound-Induced Intracerebral Hemorrhage”,
    Nanomedicine, 7, 1029-1043 (2012). (doi: 10.2217/nnm.12.2)

  3. Vong, L.B., Tomita, T., Yoshitomi, T., Matsui, H., Nagasaki, Y.
    “An Orally Administered Redox Nanoparticle that Accumlates in the Colonic Mucosa and Reduces Colitis in Mice”,
    Gastroenterology, 143, 1027-1036 (2012). (doi:10.1053/j.gastro.2012.06.043)

  4. Yoshitomi, T., Hirayama, A., Nagasaki, Y.
    “The ROS Scavenging And Renal Protective Effects of Ph-Responsive Nitroxide Radical-Containing Nanoparticles”,
    Biomaterials, 32, 8021-8028 (2011).

  5. Marushima, A., Tsurusima, H., Yoshitomi, T., Toh, K., Hirayama, A., Nagasaki, Y., Matumura, A.,
    “Newly Synthesized Radical-Containing Nanoparticles (RNP) Enhance Neuroprotection after Cerebral Ischemia-Reperfusion Injury”,
    Neurosurgery, 68, 1418-1426 (2011).

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